Cumulative Success and Live Birth Rates
We explain the difference between first-transfer and cumulative success while keeping positive pregnancy and live birth as separate metrics.
Our Cumulative Success Rates
We present positive pregnancy and live birth outcomes separately.
First Attempt and Cumulative Outcome
We compare the first embryo transfer outcome with cumulative positive pregnancy after a maximum of three transfers.
Positive Pregnancy and Live Birth
Achieving a positive pregnancy and a pregnancy resulting in a live birth are not the same outcome.
Cumulative positive pregnancy
Cumulative live birth: 73%
Cumulative positive pregnancy
Cumulative live birth: 68%
Cumulative Outcomes by Treatment
Oocyte and Embryo Donation Age 45+
What Does Cumulative Success Mean?
The outcome of the first embryo transfer.
Subsequent embryos available during the treatment journey may be included in the assessment.
The overall clinical outcome reached at the end of the defined transfer process.
A separate and later clinical outcome metric than positive pregnancy.
Questions about cumulative success and live birth
Cumulative success considers not only the first embryo transfer, but also the outcomes of subsequent transfers within the defined treatment journey. In this dataset, cumulative positive pregnancy is assessed after a maximum of 3 ETs.
The first transfer reflects only the outcome of the first embryo transfer. A cumulative rate may include subsequent transfers during the treatment journey and can therefore show a higher overall outcome.
In the Donor group, first-transfer positive pregnancy is 77%, while cumulative positive pregnancy after a maximum of 3 ETs is 90.7%.
In the IVF group, first-transfer positive pregnancy is 72.7%, while cumulative positive pregnancy after a maximum of 3 ETs is 89.7%.
Positive pregnancy is an earlier outcome showing that pregnancy has been established. Live birth is a later endpoint in the pregnancy journey. Pregnancy losses and other biological or clinical factors can therefore result in a lower live birth rate.
In the Ventus IVF data presentation, the cumulative live birth rate is 73% for the Donor group and 68% for the IVF group.
The source dataset defines the cumulative outcome after a maximum of 3 ETs; fresh and frozen transfer breakdowns are not shown separately in this public dataset. Therefore, no separate sub-rate is generated on the website.
Public pages present clinical outcomes as percentages. The record volumes underlying the calculations are maintained in the internal dataset; sample size is taken into account in age-based statistical balancing.
No. A cumulative clinical rate summarises the historical outcomes of a patient group. An individual treatment outcome can vary according to the patient's biological and clinical characteristics.