IVF
Average female age35
REAL CLINICAL DATA · FROM PATIENT RECORDS
IVF Success Rates by Age
We review cumulative success outcomes by age group without mixing the IVF and donor record groups.
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Outcomes calculated from actual clinical patient records
Age groups are shown as they are maintained in the source clinical data structure.
Cumulative outcome first
REAL CLINICAL DATA
Our Cumulative Success Rates
Before moving to age breakdowns, we show the overall cumulative outcomes of the treatment journey.
Donor Group
Cumulative positive pregnancy
90.7%
IVF Group
Cumulative positive pregnancy
89.7%
Donor Group
Cumulative live birth
73%
IVF Group
Cumulative live birth
68%
Age breakdown
Age-Adjusted Cumulative Positive Pregnancy Rates
In the source clinical records, age data are maintained within IVF and donor groups. To reduce small-sample effects, this chart displays sample-size-balanced cumulative rates.
Small-sample adjustment in age rates
When patient/ET counts in an age group are low, a raw result can look misleadingly sharp, such as 100%. In this chart, age-based rates are balanced toward the relevant group's overall cumulative outcome according to sample size.
Main clinical outcomes were not changed
Donor group cumulative positive pregnancy 90.7%, IVF group 89.7%; cumulative live birth rates are respectively 73% and 68% and are preserved exactly as the actual main group outcomes.
Notable special clinical data
Oocyte and Embryo Donation Age 45+
In the special patient group aged 45 and over, we separately examine the difference between the first attempt and cumulative outcome.
● Average female age: 48
72.5%Positive pregnancy on first attempt
84.5%Cumulative positive pregnancy
64%Cumulative live birth
The results represent clinical records for the relevant oocyte and embryo donation group; they do not represent the same individual probability for every 48-year-old patient.
Age alone does not explain success
Particularly in donation treatments, the oocyte or embryo source can change the impact of female age compared with conventional IVF.
How should high percentages be interpreted?
A group's clinical percentage should not be directly converted into an individual patient's personal chance of success. Treatment type and patient characteristics should be evaluated together.
Treatment and age relationship
Average Female Ages Across Treatment Groups
Egg Donation
Average female age42
Sperm Donation
Average female age30
Embryo Donation
Average female age42
A system that does not leave success to chance
Laboratory and Technology Processes
Although age is important, treatment outcome does not depend on age alone. Clinical and laboratory processes must be assessed together.
Artificial Intelligence
Provides additional data for embryological assessment.
EmbryoScope+
Supports monitoring embryo development over time.
VOC Control
Contributes to control of laboratory environmental conditions.
CAP
A standardised approach supporting the laboratory quality system.
Frequently asked questions
Questions about age and success rates
In the source clinical data, outcomes are maintained by age band and main treatment group. The age-based web chart shows balanced cumulative positive pregnancy rates to reduce small-sample effects.
When the sample is small, all observations in an age group may be positive, producing a raw percentage of 100%. This does not mean a new patient has a 100% chance of success.
The adjusted rate is a statistical presentation that reduces extreme variation in small age groups by drawing the raw age-group rate toward the relevant main group's overall cumulative rate in proportion to sample size.
The web presentation uses the formula (n × raw rate + 20 × overall group rate) / (n + 20). Here, n represents the number of records/ETs in the relevant age group. The overall group rate remains fixed at 90.7% for Donor and 89.7% for IVF.
No. The Donor group's 90.7% and IVF group's 89.7% cumulative positive pregnancy rates are preserved unchanged as the actual main group outcomes. Balancing is used only in presenting the age breakdown.
In the special group with an average female age of 48, positive pregnancy on the first attempt is 72.5%, cumulative positive pregnancy is 84.5%, and cumulative live birth is 64%.
The 45+ special section shows a defined oocyte and embryo donation patient group. The 45+ rate in the Donor age chart shows the age breakdown of the broader main record group and a rate balanced according to sample size. Because the scopes differ, the values are not expected to be identical.
No. Age is an important factor, but it should be considered together with oocyte or embryo source, ovarian reserve, sperm factors, embryo development and treatment type.
In small groups, a single positive or negative outcome can cause a large percentage change. For this reason, age breakdowns with small samples should be interpreted alongside the overall group outcome and sample size rather than from the raw percentage alone.
Success data centre